DNA Ligases: Progress and Prospects
نویسندگان
چکیده
منابع مشابه
Antisense DNA and RNA: progress and prospects.
Using antisense DNA or RNA fragments to block the expression of selected genes, and thereby assess their function, is a powerful new tool for the molecular biolo gist. It is an approach that promises to be particularly useful in higher eukaryotes, where the genetic tools ap plicable to yeast and bacteria are not available. There are also obvious therapeutic implications in the use of antisens...
متن کاملAntisense DNA and RNA: progress and prospects
Using antisense DNA or RNA fragments to block the expression of selected genes, and thereby assess their function, is a powerful new tool for the molecular biolo gist. It is an approach that promises to be particularly useful in higher eukaryotes, where the genetic tools ap plicable to yeast and bacteria are not available. There are also obvious therapeutic implications in the use of antisens...
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1 Department of Surgery, Scott & White Memorial Clinic and Hospital, Temple, Texas, United States of America, 2 Department of Veterinary Pathobiology, Texas A&M University, College Station, Texas, United States of America, 3 Department of Microbial and Molecular Pathogenesis, Texas A&M Health Science Center College of Medicine, College Station, Texas, United States of America, 4 Department of P...
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DNA ligases are Mg++-dependent enzymes that catalyze the formation of phosphodiester bonds at single-strand breaks in double-stranded DNA (for review and main references up to 1992, see Engler and Richardson 1982; Lindahl and Barnes 1992). The first step in the reaction is the formation of a covalent enzyme/adenylate intermediate. DNA ligases from eukaryotes, archaea, and viruses employ ATP as ...
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Lipases are the most versatile industrial enzymes and are known to bring about a range of bioconversion reactions. This compendium throws light on the developments in the field of fermentation of lipases and their scale up. Recently, interests have been shown on solid-state fermentation of lipases in order to facilitate the use of low cost agricultural wastes as substrates. Whole cell immobiliz...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2009
ISSN: 0021-9258
DOI: 10.1074/jbc.r900017200